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- J Ayensa-Jimenez, M Perez-Aliacar, M Doweidar, E Gaffney,
M Doblare, An overview from physically-based to data-driven
approaches of the modelling and simulation of glioblastoma
progression in microfluidic devices,, Archives of
Computational Methods in Engineering, In Press.
- JR Crawshaw, EA Gaffney, M Gertz, PK Maini, and A Caruso,
Modelling the Ocular Pharmacokinetics and Pharmacodynamics
of
Ranibizumab for Improved Understanding and Data Collection
Strategies
in Ocular Diseases, Investigative
Ophthalmology & Visual Science, 66:20 (2025).
- P Lamirande, EA Gaffney, M Gertz, PK Maini, JR Crawshaw
and
A Caruso. A first passage model of intravitreal drug
delivery and
residence time - influence of ocular geometry, individual
variability,
and injection location, Investigative
Ophthalmology & Visual
Science, 65:21 (2024).
- C Moreau, BJ Walker, RN Poon, D Soto, DI Goldman, E.
Gaffney, and KY Wan. Minimal design of a synthetic cilium, Physical
Review Research 6 (4), L042061 (2024).
- V Klika, E Gaffney, PK. Maini, On the speed of propagation
in Turing patterns for reaction-diffusion systems, Physica
D, 467, 134268, 2024.
- JP Whiteley, CP Brown, EA Gaffney, Sensitivity of
cartilage mechanical behaviour to spatial variations in
material properties, Journal of the Mechanical Behavior of
Biomedical Materials 156, 106575, (2024).
- AL Krause, EA Gaffney, TJ Jewell, V Klika, BJ Walker,
Turing instabilities are not enough to ensure pattern
formation, Bulletin of Mathematical Biology, 86:21
(2024).
- A Diez, AL Krause, PK Maini, EA Gaffney, S Seirin-Lee,
Turing pattern formation in reaction-cross-diffusion systems
with a
bilayer geometry, Bulletin of Mathematical Biology 86, 13
(2024).
- MP Dalwadi, C Moreau, EA Gaffney, K Ishimoto, BJ Walker,
Generalised Jeffery's equations for rapidly spinning
particles. Part 1.
Spheroids, Journal of Fluid Mechanics, 979:A1 (2024)
- MP Dalwadi, C Moreau, EA Gaffney, K Ishimoto, BJ Walker,
Generalised Jeffery's equations for rapidly spinning
particles. Part 2.
Helicoidal objects with chirality, Journal of Fluid Mechanics, 979:A2 (2024).
- TJ Jewell, AL Krause, PK Maini, EA Gaffney, Patterning of
nonlocal transport models in biology: the impact of spatial
dimension, Mathematical Biosciences, 366:109093
(2023)
- J Ayensa-Jimenez, MH Doweidar, EA Gaffney, M Doblare, A
mathematical modelling study of chemotactic dynamics in
cell cultures: the impact of spatio-temporal heterogeneity,
Bulletin of Mathematical Biology, 85:98
(2023).
- M Dvoriashyna, A Foss, E Gaffney, R Repetto, Mathematical
modelling of ocular epithelial transport: a review, Modeling and Artificial Intelligence in
Ophthalmology, 5:1-17 (2023).
- K Ishimoto, EA Gaffney, DJ Smith, Squirmer hydrodynamics
near a periodic surface topography, Frontiers in cell and developmental
biology 11, 1123446, 2023
- BJ Walker, K Ishimoto, EA Gaffney, Hydrodynamic
slender-body theory for local rotation at zero
Reynolds number, Physical Review Fluids 8 (3), 034101
(2023)
-
JD Glover, ZR Sudderick, BBJ Shih, C Batho-Samblas, L
Charlton, ..., EA Gaffney, ...., D Headon. The developmental
basis of fingerprint pattern formation and
variation, Cell 186 (5), 940-956. (2023)
- BJ Walker, K Ishimoto, EA Gaffney, Systematic
parameterizations of minimal models of
microswimming, Physical Review Fluids 8 (3), 034102, 2023
-
AL Krause, EA Gaffney, BJ Walker, Concentration-Dependent
Domain Evolution in
Reaction-Diffusion Systems, Bulletin of Mathematical Biology 14,
(2023)
- V
Klika, EA Gaffney, Upscaling the Poisson-Nernst-Planck
equations for
ion transport in weakly heterogeneous charged porous media,
Applied
Mathematics Letters, 137, 108482, (2023).
- DB
de Souza, HA Araujo, GC Duarte-Filho, EA Gaffney, FAN
Santos, and EP Raposo,
Fock-space approach to stochastic
susceptible-infected-recovered models, Phys.
Rev. E (2022) 106:014136
- LV Brown, MC Coles, M McConnell, AV Ratushny, EA Gaffney,
Analysis
of cellular kinetic models suggest that physiologically
based model
parameters may be inherently, practically unidentifiable, Journal of Pharmacokinetics and
Pharmacodynamics (2022) 49:539-556
- A Sargood, EA Gaffney, AL Krause, Fixed and Distributed
Gene
Expression Time Delays in Reaction-Diffusion Systems, Bull. Math Bio (2022) 84:98, 29 pages.
- L Brown, J Wagg, R Darley, A van Hateren, T Elliott, E
Gaffney, M Coles, De-risking clinical trial failure through
mechanistic
simulation, Immunotherapy Advances, (2022) 2:1-15.
- M Dvoriashyna, AJE Foss, EA Gaffney, R Repetto, A
mathematical model of aqueous humor production and
composition, Investigative
Ophthalmology and Visual Science, (2022) 63:1-11.
- BJ Walker, K Ishimoto, C Moreau, EA Gaffney, MP Dalwadi,
Emergent
rheotaxis of shape-changing swimmers in Poiseuille flow, J.
Fluid Mechanics
(2022), doi.org/10.1017/jfm.2022.474
- EA Gaffney, MP Dalwadi, C Moreau, K Ishimoto, BJ Walker,
Canonical
orbits for rapidly deforming planar microswimmers in shear
flow, Physical
Review Fluids (2022) 7, L022101
- JE Jansen, D Aschenbrenner, HH Uhlig, MC Coles, EA
Gaffney, A
method for the inference of cytokine interaction networks, PLoS computational
biology (2022) 18, e1010112
- BJ Walker, K Ishimoto, EA Gaffney, C Moreau, The control
of
particles in the Stokes limit, Journal of Fluid Mechanics
(2022), doi.org/10.1017/jfm.2022.253
- JP Whiteley, CP Brown, EA Gaffney, Modelling articular
cartilage: the relative motion of two
adjacent poroviscoelastic layers, Mathematical Medicine and
Biology: A Journal of the IMA, (2022), doi: 10.1093/imammb/dqac005
- BJ Walker, K Ishimoto, EA Gaffney, C Moreau, MP Dalwadi,
The
effects of rapid yawing on simple swimmer models and planar
Jeffery's
orbits, Physical Review Fluids, (2022) 7, 023101.
- AL Krause, EA Gaffney, PK Maini, V Klika, Modern
perspectives on near-equilibrium analysis of Turing systems,
Phil. Trans. R. Soc. A (2021) 379:20200268
- AL Krause, EA Gaffney, PK Maini, V Klika, Introduction to
recent progress and open frontiers in Turing's theory of
morphogenesis, Phil. Trans. R. Soc. A (2021) 379:20200280
- AE Kmieciak, LV Brown, MC Coles, J Wagg, A Phipps, EA
Gaffney, Predicted limited redistribution of T cells to
secondary
lymphoid tissue correlates with increased risk of
haematological
malignancies in asplenic patients, Scientific Reports (2021) 11:16394.
- C Moreau, K Ishimoto, EA Gaffney, BJ Walker, Control and
controllability of microswimmers by a shearing flow, Royal Society Open Science (2021),
8:211141
- EA Gaffney, K Ishimoto, BJ Walker, Modelling Motility: The
Mathematics of Spermatozoa, Frontiers in Cell and Developmental
Biology, (2021) 9:710825
- AL Krause, V Klika, PK Maini, D Headon, EA Gaffney,
Isolating Patterns in Open Reaction-Diffusion Systems, Bull. Math. Bio. (2021),
83:doi10.1007/s11538-021-00913-4
- V Tokarova, AS Perumal, M Nayak, H Shum, O Kaspar, K
Rajendran, M Mohammadi, C Tremblay, EA Gaffney, S Martel, DV
Nicolau,
Patterns of bacterial motility in microfluidics-confining
environments, PNAS (2021), 118:2013925118
- TE Woolley, AL Krause, EA Gaffney, Bespoke Turing Systems,
Bull. Math. Bio. (2021)
83:doi10.1007/s11538-021-00870-y
- BJ Walker, K Ishimoto, EA Gaffney, Regularised non-uniform
segments and efficient no-slip elastohydrodynamics, Journal of Fluid Mechanics (2021), 915,
doi:10.1017/jfm.2021.139.
- LV Brown, EA Gaffney, A Ager, J Wagg, MC Coles,
Quantifying the limits of CAR T-cell delivery in mice and
men, Journal of The Royal Society Interface
(2021) 18:0201013 doi:10.1098/rsif.2020.1013
- D Aschenbrenner, M Quaranta, S Banerjee, N Ilott, J
Jansen,
BA Steere, Y Chen, S Ho, K Cox, Oxford IBD Cohort
Investigators, CV
Arancibia-Carcamo, M Coles, E Gaffney, S Travis, LA Denson,
S
Kugathasan, J Schmitz, F Powrie, S Sansom, HH Uhlig,
Deconvolution of
monocyte responses in inflammatory bowel disease reveals an
IL-1
cytokine network that regulates IL-23, Gut (2021), 70:1023-1036.
- BJ Walker, K Ishimoto, EA Gaffney, Efficient simulation of
filament elastohydrodynamics in three dimensions, Physical Review Fluids (2020), 5:123103,
doi:10.1103/PhysRevFluids.5.123103
- GC Duarte, FAN Santos, EA Gaffney, Fock-space methods for
diffusion: Capturing volume exclusion via Fermionic
statistics, Physical Review E (2020), 102:052101,
doi:10.1103/PhysRevE.102.052101
- AL Krause, V Klika, J Halatek, PK Grant, TE Woolley, N
Dalchau, EA Gaffney, Turing Patterning in Stratified
Domains, Bull. Math. Bio. (2020), 82,
doi:10.1007/s11538-020-00809-9.
- K Ishimoto, EA Gaffney, BJ Walker. Regularized
representation of bacterial hydrodynamics. Physical Review Fluids (2020),
doi:10.1103/PhysRevFluids.5.093101
- S Seirin-Lee, EA Gaffney, A Dawes, CDC-42 interactions
with
Par proteins are critical for proper patterning in
polarization, Cells (2020), DOI: 10.3390/cells9092036.
- SN Calver, EA Gaffney, EJ Walsh, WM Durham, JM Oliver, On
the thin-film asymptotics of surface-tension-driven
microfluidics, Journal of Fluid Mechanics (2020), 901,
10.1017/jfm.2020.532.
- BJ Walker, K Ishimoto, EA Gaffney, A regularised
slender-body theory of non-uniform filaments, Journal of Fluid Mechanics (2020),
899:10.1017/jfm.2020.434
- A Osojnik, EA Gaffney, M Davies, JWT Yates, HM Byrne,
Identifying and characterising the impact of excitability in
a
mathematical model of tumour-immune interactions, Journal of Theoretical Biology (2020),
501:110250
- MF Adamer, HH Harrington, EA Gaffney, TE Woolley, Coloured
Noise from Stochastic Inflows in Reaction-Diffusion Systems,
Bull. Math. Bio. (2020), 82,
10.1007/s11538-020-00719-w
- BJ Walker, S Phuyal, K Ishimoto, CK Tung, EA Gaffney,
Computer-assisted beat-pattern analysis and the flagellar
waveforms of
bovine spermatozoa, Royal Society Open Science (2020) 7:200769
- AL Krause, V
Klika, TE Woolley, EA Gaffney, From One Pattern into
Another: Analysis
of Turing Patterns in Heterogeneous Domains via WKBJ, J. Roy Soc.
Interface (2020) 20190621.
- M Dvoriashyna, AJE Foss, EA Gaffney, R Repetto,
Fluid and Solute Transport across the Retinal Pigment
Epithelium: a
Theoretical Model, J. Roy Soc. Interface (2020) 20190735
- S Egginton, RWP Kissane, AA Al-Shammari, and EA Gaffney,
Quantifying fiber type-specific local capillary
supply, J. Applied Physiology, (2020) 128:458-459.
- JP
Whiteley, EA Gaffney, Modelling the Inclusion of Swelling
Pressure in a
Tissue Level Poroviscoelastic Model of Cartilage
Deformation,
Mathematical Medicine And Biology: A Journal Of The IMA,
(2020) https://doi.org/10.1093/imammb/dqaa001
- BJ Walker, K Ishimoto, H Gadelha, EA Gaffney, Filament
mechanics in half-space via regularised Stokeslet segments,
Journal of
Fluid Mechanics (2019), 879:803-833.
- JE Jansen, EA Gaffney, J Wagg, MC Coles, Combining
Mathematical Models With Experimentation to Drive Novel
Mechanistic
Insights Into Macrophage Function, Frontiers In Immunology (2019)
10.3389/fimmu.2019.01283
- BJ Walker, K Ishimoto, EA Gaffney, Pairwise hydrodynamic
interactions of synchronized spermatozoa, Physical Review
Fluids, (2019) 093101.
- BJ Walker, RJ Wheeler, K Ishimoto, EA Gaffney, Boundary
behaviours of Leishmania mexicana: A hydrodynamic simulation
study, Journal of Theoretical Biology (2019)
462:311-320.
- H Gadelha, EA Gaffney, Flagellar ultrastructure suppresses
buckling instabilities and enables mammalian sperm
navigation in
high-viscosity media, J Roy Soc interface (2019),
https://doi.org/10.1098/rsif.2018.0668
- WKW Ho, L Freem, D Zhao, KJ Painter, TE Woolley, EA
Gaffney, MJ McGrew, A Tzika, MC Milinkovitch, P Schneider, A
Drusko, F
Matthaus, JD Glover, KL Wells, JA Johansson, MG Davey, HM
Sang, M
Clinton, DJ Headon, Feather arrays are patterned by
interacting
signalling and cell density waves, PLOS Biology (2019), 17, DOI:
10.1371/journal.pbio.3000132.
- V Klika and JP Whiteley and CP Brown and EA Gaffney, The
combined impact of tissue heterogeneity and fixed charge for
models of
cartilage: the one-dimensional biphasic swelling model
revisited,
Biomechanics and Modeling in Mechanobiology, (2019) doi: 10.1007/s10237-019-01123-7.
- Abdullah A Al-Shammari, Roger WP Kissane, Simon Holbek,
Abigail Louise Mackey, Thomas R Andersen, Eamonn A Gaffney,
Michael
Kjaer, Stuart Egginton, Integrated method for quantitative
morphometry
and oxygen transport modeling in striated muscle, J Appl Physiol (2019) 126(3):544-557
- BJ Walker, RJ Wheeler, K Ishimoto, EA Gaffney, Response of
monoflagellate pullers to a shearing flow: A simulation
study of
microswimmer guidance, Physical Review E (2018) 063111
- Kenta Ishimoto, Eamonn A Gaffney, Hydrodynamic Clustering
of Human Sperm in Viscoelastic Fluids, Scientific reports (2018), 15600.
- M Dvoriashyna, AJE Foss, EA Gaffney, OE
Jensen, OE, R Repetto, Osmotic and Electroosmotic Fluid
Transport
across the Retinal Pigment Epithelium: a Mathematical Model,
Journal of Theoretical Biology (2018)
456:233-248.
- LV Brown, EA Gaffney, J Wagg, MC Coles, Applications
of Mechanistic Modelling to Clinical and Experimental
Immunology:
An emerging technology to accelerate immunotherapeutic
discovery and
development, Clinical and Experimental Immunology,
(2018) 193:284-292.
- V. Klika, M Kozak, EA Gaffney, Domain Size Driven
Instability:
Self-Organisation in Systems with Advection, SIAM Journal on Applied
Mathematics (2018), 78(5), 2298-2322.
- K Ishimoto, EA Gaffney, An elastohydrodynamical
simulation study of fillament and spermatozoan swimming
driven by
internal couples, IMA J. Appl. Math (2018), 83:655-679.
- LA Hutton-Smith, EA Gaffney, HM Byrne, A Caruso, PK
Maini, and NA Mazer, Theoretical Insights Into the Retinal
Dynamics of
VEGF in Patients Treated with Ranibizumab, Based on an
Ocular
Pharmacokinetic/Pharmacodynamic Model, Molecular Pharmaceutics, (2018),
15:2770-2784.
- DL Humphries, JA
Grogan, EA Gaffney, The mechanics of phantom Mikado
networks, Journal of Physics Communications (2018)
2, UNSP 055015
- AL Krause, V Kilika, TE Woolley, EA Gaffney, Heterogeneity
induces spatiotemporal oscillations in reaction-diffusion
systems, Physical Review E (2018), 97, 052206
- C Willshire, AJ Bron, EA. Gaffney, EI Pearce, Basal Tear
Osmolarity as a metric to estimate body hydration and dry
eye severity, Progress in Retinal and Eye Research
(2018) 64:56-64.
- K Ishimoto, H Gadelha,
EA Gaffney, DJ Smith, JC Kirkman Brown, Human sperm swimming
in a high viscosity mucus analogue, J. Theoretical Biology, (2018) 446:1-10.
- L Brown, EA Gaffney, J. Wagg, M Coles, An In Silico Model
of Cytotoxic T-Lymphocyte Activation in the Lymph Node
Following Short
Peptide Vaccination, J. Royal Society Interface (2018) 15
20180041; DOI: 10.1098/rsif.2018.0041
- TE
Woolley, J Belmonte-Beitia, G F Calvo, JW Hopewell, EA
Gaffney, B
Jones, Changes in the retreatment radiation tolerance of the
spinal
cord with time after the initial treatment, International Journal of
Radiation Biology, (2018) 94:515-531
- PA
Roberts, EA Gaffney, JP Whiteley, PJ
Luthert, AJE Foss, HM Byrne, Predictive
Mathematical Models for the Spread and Treatment of
Hyperoxia-induced
Photoreceptor Degeneration in Retinitis, Investigative Ophthalmology
& Visual Science, (2018) 59:1238-1249
- K Ishimoto, EA Gaffney, Boundary element methods for
particles and microswimmers in a linear viscoelastic fluid,
Journal of Fluid Mechanics (2017)
831:228-251.
- V
Klika, EA Gaffney, History dependence and the continuum
approximation
breakdown: the impact of domain growth on Turing's
instability, Proc Roy Soc A (2017) 20160744.
- LA Hutton-Smith, EA
Gaffney, HM Byrne, PK Maini, K Gadkar, NA Mazer, Ocular
Pharmacokinetics of Therapeutic Antibodies Given by
Intravitreal
Injection: Estimation of Retinal Permeabilities Using a
3-Compartment
Semi-Mechanistic Model, Mol. Pharm (2017), 14:2690-2698.
- TE
Woolley, EA Gaffney, A. Goriely, Random blebbing motion: A
simple model
linking cell structural properties to migration
characteristics Phys Rev E (2017) 96, 012409
-
PA Roberts, EA Gaffney, PJ Luthert, AJE Foss, HM Byrne,
Mathematical
models of retinitis pigmentosa: The oxygen toxicity
hypothesis, J. Theoretical Biology, (2017) 425:53-71.
- M.A.
Gilbert, S.M. White, J.M. Bullock, E.A. Gaffney, Speeding Up
The
Simulation of Population Spread Models, Methods in Ecology and
Evolution, (2017) 8:501-510.
- K Ishimoto, H Gadelha,
EA Gaffney, DJ Smith, JC Kirkman Brown, Coarse-Graining the
Fluid Flow
around a Human Sperm, Physical Review Letters (2017) 118:124501
- Reply to Baveye and Darnault: Useful models are simple and
extendable, KZ Coyte, H Tabuteau, EA Gaffney, KR Foster, WM
Durham, PNAS, (2017) 114:E2804-E2805.
- Y.
Chen, M. Chen , EA Gaffney, CP Brown, Effect of crosslinking
in
cartilage-like collagen microstructures, Journal of the Mechanical
Behavior of Biomedical Materials, (2017) 66:138-143.
- DL Humphries, JA
Grogan, EA Gaffney, Mechanical Cell-Cell Communication in
Fibrous
Networks: The Importance of Network Geometry, Bulletin of Mathematical Biology (2017)
79:498-524.
- Microbial
competition in porous environments can select against rapid
biofilm
growth, KZ Coyte, H Tabuteau, EA Gaffney, KR Foster, WM
Durham, PNAS, (2017) 114:E110-E170.
- F.
Yi, EA Gaffney, S Seirin Lee, The Bifurcation Analysis of
Turing
Pattern Formation Induced by Delay and Diffusion in The
Schnakenberg
System, Journal Discrete and Continuous Dynamical
System B, (2017) 247:647-668.
- K
Ishimoto, EA Gaffney, Mechanical tuning of mammalian sperm
behaviour by
hyperactivation, rheology and substrate adhesion: a
numerical
exploration, J. Royal Society Interface (2016),
13:20160633.
- LG Hutchinson, H-J
Mueller, EA Gaffney, PK Maini, J Wagg, A Phipps, C Boetsch,
HM Byrne, B
Ribba, Modeling Longitudinal Preclinical Tumor Size Data to
Identify
Transient Dynamics in Tumor Response to Antiangiogenic
Drugs, CPT
Pharmacometrics Syst. Pharmacol (2016), doi:10.1002/psp4.12142
- LA Hutton-Smith, EA
Gaffney, HM Byrne, PK Maini, D Schwab, NA Mazer, A
mechanistic model of
the intravitreal pharmacokinetics of large molecules and the
pharmacodynamic suppression of ocular vascular endothelial
growth
factor levels by ranibizumab in patients with neovascular
age-related
macular degeneration, Molecular pharmaceutics (2016) 13:2941-50.
- LG Hutchinson, EA
Gaffney, PK Maini, J Wagg, A Phipps, HM Byrne, Vascular
phenotype
identification and anti-angiogenic treatment recommendation:
A
pseudo-multiscale mathematical model of angiogenesis, Journal of
Theoretical Biology (2016) 398:162-180.
- PA Roberts, EA Gaffney, PJ Luthert, AJE Foss, HM Byrne,
Retinal Oxygen Distribution and the Role of Neuroglobin, Journal of Mathematical Biology, (2016)
73:1-38.
- V Klika, EA Gaffney*,
YC Chen, CP Brown, An overview of multiphase cartilage
mechanical
modelling and its role in understanding function and
pathology, Journal
of The Mechanical Behavior Of Biomedical Materials (2016)
62: 139-157
[*Equal first authors].
- PA
Roberts, EA Gaffney, PJ Luthert, AJE Foss, HM Byrne,
Mathematical And
Computational Models Of The Retina In Health, Development
And Disease, Progress in Retinal And Eye Research
(2016) 53:48-69.
- K Ishimoto, J Cosson, EA Gaffney, A Simulation Study of
Sperm Motility Hydrodynamics Near Fish Eggs and Spheres, Journal of Theoretical Biology, 389:
187-197 (2016).
- FAN Santos, H Gadelha,
EA Gaffney, Fock space, symbolic algebra and analytical
solutions for
small stochastic systems, Physical Review E, (2015) 062714.
- H Shum, EA Gaffney, Hydrodynamic analysis of flagellated
bacteria swimming in corners of rectangular channels Physical Review E 92: 063016 (2015).
- TE
Woolley, EA Gaffney, A. Goriely, Membrane shrinkage and
cortex
remodelling are predicted to work in harmony to retract
blebs, Royal Society Open Science, (2015).DOI:
10.1098/rsos.150184, 15 pages.
- Duffy
B, Thiyagalingam J, Walton S, Smith DJ, Trefethen A,
Kirkman-Brown JC,
Gaffney EA, Chen M. Glyph-Based Video Visualization for
Semen Analysis. IEEE Trans Vis Comput Graph. (2015) 21:
980-993
- D
Hauton, J Winter, AA Al-Shammari, EA Gaffney, RD Evans, S
Egginton,
Maternal hypoxia decreases capillary supply and increases
metabolic
inefficiency leading to divergence in myocardial oxygen
supply and
demand, PLOS One (2015), DOI:
10.1371/journal.pone.0127424
- H Shum, EA Gaffney, Hydrodynamic analysis of flagellated
bacteria swimming near one and between two no-slip plane
boundaries, Physical Review E (2015) 91:033012
- K. Ishimoto, EA Gaffney, Fluid flow and sperm guidance: a
simulation study of hydrodynamic sperm rheotaxis, Journal of the Royal Society
Interface(2015), 12:20150172.
- D Hauton, J Winter, AA Al-Shammari, EA Gaffney, RD Evans,
S Egginton, Changes
to both cardiac metabolism and performance accompany acute
reductions in
functional capillary supply, Biochimica et Biophysica Acta
(BBA)-General Subjects, (2015) 1850:681-690.
- K Korvasov, EA Gaffney, PK Maini, MA Ferreira, V Klika,
Investigating
the Turing conditions for diffusion-driven instability in
the presence of a
binding immobile substrate, Journal of Theoretical Biology, (2015)
367:286-195.
- EA Gaffney, S Seirin Lee*, The Sensitivity of Turing
Self-Organisation
to Biological Feedback Delays: 2D Models of Fish
Pigmentation, Mathematical Medicine and Biology, (2015)
32:56-78. [*Equal First Authors]
- MA
Gilbert, EA Gaffney, JM Bullock, SM White, Spreading speeds
for plant
populations in landscapes with low environmental variations,
Journal of
Theoretical Biology (2014), 363:436-452
- EH Ooi, DJ Smith, H Gadelha, EA Gaffney, J. Kirkman-Brown
The mechanics
of hyperactivation in adhered human sperm, Royal Society Open Science 2014, doi
10.1098/rsos.140230
- JB McGillen, CJ Kelly, A Martinez-Gonzalez, NK Martin, EA
Gaffney, PK
Maini, Victor M Perez-Garcia, Glucose-lactate metabolic
cooperation in cancer:
Insights from a spatial mathematical model and implications
for targeted
therapy, Journal of Theoretical Biology (2014)
361:190-203
- K Ishimoto, EA Gaffney, A study of spermatozoan swimming
stability near a surface. Journal of Theoretical Biology (2014) 360
187-199.
- TE
Woolley, PK Maini and EA Gaffney, Is pigment cell pattern
formation in
zebrafish a game of cops and robbers? Pigment Cell & Melanoma Research
(2014) 27:686-687.
- K Ishimoto, EA Gaffney, Swimming efficiency of spherical
squirmers: Beyond the Lighthill theory. Phys Rev E (2014), 90 012704
- TE Woolley, EA Gaffney, SL Waters, JM Oliver, RE Baker, A
Goriely, Three mechanical models for blebbing and
multi-blebbing, IMA
Journal of Applied Mathematics (2014) 79:636-660.
- AA
Al-Shammari, EA Gaffney, S Egginton, Modelling capillary
oxygen supply
capacity in mixed muscles: Capillary domains revisited, Journal of
Theoretical Biology, (2014) 356:47-61
- DC Markham, MJ Simpson, PK Maini, EA Gaffney, RE Baker,
Comparing methods for modelling spreading cell fronts Journal of Theoretical Biology (2014)
353:95-103.
- S
Manzano, EA Gaffney, M Doblare, AH Doweidar, Cartilage
Dysfunction in
ALS Patients as Side Effect of Motion Loss: 3D
Mechano-Electrochemical
Computational Model, Biomed Research International 179070
(2014)
- JB McGillen, EA Gaffney, NK Martin, PK Maini, A general
reaction-diffusion model of acidity in cancer invasion, J. Math. Biol. (2014), 68:1199-1224
- MA
Gilbert, SM White, JM Bullock, EA Gaffney, Spreading speeds
for stage
structured plant populations in fragmented landscapes, Journal of
Theoretical Biology (2014), 349:135-49.
- TE
Woolley, EA Gaffney, JM Oliver, RE Baker, SL Waters, A
Goriely,
Cellular blebs: pressure-driven, axisymmetric, membrane
protrusions, Biomechanics and Modeling in
Mechanobiology (2014), 13:463-476
- K Ishimoto, EA Gaffney, Squirmer dynamics near a boundary.
Phys Rev E 88, 062702 (2013).
- DC
Markham, MJ Simpson, PK Maini, EA Gaffney, RE Baker,
Incorporating
spatial correlations into multispecies mean-field models, Phys. Rev
E88, 052713 (2013).
- H. Gadelha, E. A. Gaffney, and A. Goriely, The counterbend
phenomenon in flagellar axonemes and cross-linked filament
bundles, PNAS 2013 110 (30) 12180-12185.
- S.
Seirin Lee, RE Baker, EA Gaffney, SM White, Modelling Aedes
aegypti
mosquito control via transgenic and sterile insect
techniques: Endemics
and emerging outbreaks, J.
Theor. Biol. (2013), 331 p78-90.
- VS Zubkov, CJW Breward, EA Gaffney, Meniscal Fluid
Dynamics near Marx's Line, Bull. Math. Bio., (2013) 75, p1524-1543.
- J
Belmonte-Beitia, TE Woolley, JG Scott, PK
Maini, EA Gaffney, Modelling biological invasions:
Individual to
population scales at interfaces, J. Theoretical
Biology, (2013) 334:1-12.
- MP Curtis, EA Gaffney, The Three Sphere Swimmer in a
Nonlinear Viscoelastic Medium, Phys Rev E 87, 043006 (2013)
- S.
Seirin Lee, RE Baker, EA Gaffney, SM White, Optimal barrier
zones for
stopping the invasion of Aedes aegypti mosquitoes via
transgenic or
sterile insect techniques, Theor. Ecol. (2013), 6, p427-442.
- MP Curtis, JC Kirkman-Brown, TJ Connolly, EA
Gaffney, Modelling a tethered mammalian sperm cell
undergoing hyperactivation, Journal of Theoretical Biology (2012) 309,
p1-10
- EA
Gaffney, NAM Monk, RE Baker, S Seirin Lee, Reply to
Correspondence: No
Oscillations in Real Activator-Inhibitor Systems in
Accomplishing Pattern
Formation. Bull
Math Biol. (2012) 74:2268-2271.
- H Shum, EA Gaffney, The effects of flagellar
hook compliance on motility of monotrichous bacteria: a
modeling study, Physics of Fluids (2012) Volume: 24 Issue:
6 Pages: 061901 (19 pp.)
- VS Zubkov, CJW Breward, EA Gaffney, Coupling
fluid and solute dynamics within the ocular surface tear
film: a modelling
study of black line osmolarity, Bull. Math. Bio (2012) 74, p2062-93
- NK Martin, IF Robey, EA Gaffney, RJ Gillies,
RA Gatenby, PK Maini, Predicting the Safety and Efficacy of
Buffer Therapy to
Raise Tumour pHe: An Integrative Modelling Study, British J. of Cancer (2012), 7, 1280-1287.
- AA Al-Shammari, EA Gaffney, S Egginton, Re-evaluating the
Use of Voronoi Tessellations in the
Assessment of Oxygen Supply from Capillaries in Muscle. Bull. Math. Bio (2012) 74, p2204-31
- MJ Tindall, EA Gaffney, PK Maini, JP
Armitage, Theoretical insights into bacterial chemotaxis WIREs Syst Biol Med (2012) 4, p247-259.
- H Colin-Harper, TE Woolley, L Dyson, A Patel,
P Potter, RE Baker, EA Gaffney, PK Maini, PR Dash, K Patel,
Age Related changes
in speed and mechanism of adult stem cell migration, Stem Cells (2012), 30, p1182-1195.
- PK Maini, TE Woolley, RE Baker, EA Gaffney
and S Seirin Lee, Turing's model for biological pattern
formation and the
robustness problem, Interface Focus (2012), 2, p487-496
- J. McGillen, NK Martin, IF Robey, EA Gaffney,
PK Maini, Applications of mathematical analysis to tumour
acidity modelling, U.
Kyoto RIMS Kokyuroku Bessatsu, May 2012, 31-60.
- PDMH Verhaegen, J van Marle, A Kuehne, HJ
Schouten, EA Gaffney, PK Maini, E Middelkoop, PPM van
Zuijlen, Collagen bundle
morphometry in skin and scar tissue: a novel distance
mapping method provides
superior measurements compared to Fourier analysis, Journal of Microscopy, (2012) 245 p82-89.
- TE Woolley, RE Baker, EA Gaffney, PK
Maini, S Seirin-Lee, Effects of intrinsic stochasticity on
delayed
reaction-diffusion patterning systems, Phys.
Rev. E (2012) 85 051914
- V Klika, RE Baker, D Headon, EA Gaffney, The
influence of receptor-mediated interactions on
reaction-diffusion mechanisms of
cellular self-organisation, Bulletin of Mathematical Biology (2012) p
935-957.
- TE Woolley, RE Baker, EA Gaffney, PK Maini,
Stochastic reaction and diffusion on growing domains:
Understanding the
breakdown of robust pattern formation, Phys.
Rev. E 84, (2011) 046216 [16 pages]
- TE Woolley, RE Baker, EA Gaffney, PK Maini,
Influence of stochastic domain growth on pattern nucleation
for diffusive
systems with internal noise, Phys.
Rev. E 84, 041905 (2011) [13 pages]
- EAJ Boston, EA Gaffney, The influence of toxicity
constraints in models of chemotherapeutic protocol
escalation Math Med Biol (2011) 28 p357-384.
- C. Venkataraman, T. Sekimura, EA Gaffney, PK Maini,
A.Madzvamuse, Modeling
parr-mark pattern formation during the early development of
Amago trout Phys.
Rev. E 84, 041923 (2011) [13 pages]
- S Seirin Lee, EA Gaffney, RE Baker, The
dynamics of Turing patterns for morphogen-regulated growing
domains with
cellular response delays, Bulletin of Mathematical Biology, (2011),
73 p2527-2551
- TE Woolley, RE Baker, EA Gaffney, PK. Maini,
Power spectra methods for a stochastic description of
diffusion on
deterministically growing domains Phys. Rev. E (2011) 84, 021915 [15 pages]
- DJ Smith, EA Gaffney, H Shum, H Gadelha, JC
Kirkman-Brown, Comment on the Article by J. Elgeti, U. B.
Kaupp, and G. Gompper:
Hydrodynamics of Sperm Cells Near Surfaces, Biophysical J. (2011) 100(9) p2318-2320
- AJ Bron, N Yokoi, EA Gaffney, JM Tiffany, A
solute gradient in the tear meniscus. I. A hypothesis to
explain Marx's line. The Ocular Surface (2011) 9 p70-91.
- AJ Bron, N Yokoi, EA Gaffney, JM Tiffany, A
solute gradient in the tear meniscus. II Implications for
lid margin disease,
including meibomian gland dysfunction. The
Ocular Surface (2011) 9 p92-97.
- J Schofield, EA Gaffney, RA Gatenby, PK
Maini, Tumour angiogenesis: The gap between theory and
experiments, J. Theoretical Biology, (2011) 274,
p97-102.
- NK Martin, EA Gaffney, RA Gatenby, RJ
Gillies, IF Robey, PK. Maini, A Mathematical Model of Tumour
and Blood pHe
Regulation: The HCO3 /CO2 Buffering System, Math Biosci (2011) 230 p1-11.
- EA Gaffney, H Gadelha, DJ Smith, JR Blake, JC
Kirkman-Brown, Mammalian Sperm Motility: Observation and
Theory. Annual Reviews of Fluid Mechanics, (2011),
43, p501-528.
- NK Martin, EA Gaffney, RA Gatenby, PK Maini,
Tumour-Stromal Interactions in Acid-Mediated Invasion: A
Mathematical Model, Journal Of Theoretical Biology, (2010),
267, p461-470.
- NK Martin, EA Gaffney, RA Gatenby, PK Maini,
Leaky Vessels As A Potential Source Of Stromal Acidification
In Tumours, Journal Of Theoretical Biology (2010), 267
p454-460.
- S Egginton, EA Gaffney, Tissue capillary
supply - it's quality not quantity that counts!, Experimental
Physiology (2010), 95, p971-979.
- S Seirin Lee, EA Gaffney, Aberrant Behaviours
of Reaction Diffusion Self-organisation Models on Growing
Domains in the
Presence of Gene Expression Time Delays, Bulletin of Mathematical Biology (2010),
72, p2161-2179.
- H Gadelha, EA Gaffney, DJ Smith, JC
Kirkman-Brown, Nonlinear instability in flagellar dynamics:
a novel modulation
mechanism in sperm migration?, J. Royal Society Interface (2010) 7
p1689-1697.
- S Seirin Lee, EA Gaffney, NAM Monk, The
Influence of Gene Expression Time Delays on Gierer-Meinhardt
Pattern Formation
Systems, Bulletin of Mathematical Biology (2010),
72, p2139-2160.
- H Shum, EA Gaffney, DJ Smith, Modelling
bacterial behaviour close to a no-slip plane boundary: the
influence of
bacterial geometry, Proc Roy Soc A (2010) 466 p1725-1748.
- P Moreo, EA Gaffney, JM Garcia-Anzar, M
Doblare, On the modelling of biological patterns with
mechanochemical models:
insights from analysis and computation, Bulletin of Mathematical Biology (2010),
72, p400-431.
- A Madzvamuse, EA Gaffney, PK Maini, Stability
analysis of reaction-diffusion systems with time-dependent
coefficients on
growing domains, Journal Of Mathematical Biology (2010),
61, p133-164
- EA Gaffney, JM Tiffany, N Yokoi, AJ Bron, A
Mass and Solute Balance Model for Tear Volume and Osmolarity
in The Normal And
The Dry Eye, Progress in Retinal And Eye Research
(2010), 29, p59-78.
- DJ Smith, EA Gaffney, JR Blake, Mathematical
modelling of cilia-driven transport of biological fluids, Proceedings of the Royal Society A (2009),
465, p2417-2439.
- AJ Bron, N Yokoi, EA Gaffney, JM Tiffany,
Predicted Phenotypes of Dry Eye - Proposed Consequences of
its Natural History, The Ocular Surface (2009) 7, p78-92.
- DJ Smith, EA Gaffney, H Gadelha, N Kapur, JC
Kirkman-Brown, Bend propagation in the flagella of migrating
human sperm, and
its modulation by viscosity, Cell Motility & The Cytoskeleton
(2009), 66, 220-236.
- DJ Smith, EA Gaffney, JR Blake, JC
Kirkman-Brown, Human sperm accumulation near surfaces: a
simulation study, J. Fluid Mechanics (2009), 621, p289-320.
- HC Monro, EA Gaffney, Modelling chemotherapy
resistance in palliation and failed cure, J. Theoretical Biology (2009), 257,
p292-302.
- DJ Smith, EA Gaffney, JR Blake, Modelling
mucociliary clearance, Respiratory Physiology & Neurobiology
(2008) 163,
p178-188.
- RE Baker, EA Gaffney, PK Maini, Partial
differential equations for self-organization in cellular and
developmental
biology, Nonlinearity
(2008), 21, R251-290.
- DJ Smith, JR Blake, EA Gaffney, Fluid
mechanics of nodal flow due to embryonic primary cilia, Journal of The Royal Society Interface
(2008) 5, p567-573
- EA Gaffney, JK Heath, MZ Kwiatkowska, A Mass
Action Model of a Fibroblast Growth Factor Signaling Pathway
and Its
Simplification, Bulletin of Mathematical Biology (2008)
68, p99-130.
- DJ Smith, EA Gaffney, JR Blake, Discrete
cilia modelling with singularity distributions, Bulletin of Mathematical Biology (2007)
69, p1477-1510.
- DJ Smith, EA Gaffney, JR. Blake, A model of
tracer transport in airway surface liquid, Bulletin of Mathematical Biology (2007)
69, p817-836.
- DJ Smith, EA Gaffney and JR Blake, A
visco-elastic traction layer model of muco-ciliary
transport, Bulletin Mathematical Biology, (2007) 69,
p289-327.
- EA Gaffney, NAM Monk, Gene Expression Time
Delays and Turing Pattern Formation Systems, Bulletin Mathematical Biology (2006),
p99-130.
- EA Gaffney, The Mathematical Modelling of
Adjuvant Chemotherapy Scheduling: Incorporating the Effects
of Protocol Rest
Phases and Pharmacokinetics. Bulletin of Mathematical Biology (2005)
67, p563-611.
- EA Gaffney, The Application Of Matematical
Modelling To Aspects Of Adjuvant Chemotherapy Scheduling, Journal of Mathematical Biology (2004) 48,
p375-422.
- EA Gaffney, K. Pugh, PK Maini, F. Arnold,
Investigating A Simple Model Of Wound Healing Angiogenesis,
J. of Mathematical Biology (2002) 45
p337-374.
- E. Crampin, EA Gaffney, P.K. Maini, Mode
Doubling And Tripling In Reation-Diffusion Patterns On
Growing Domains: A
Piecewise Linear Model, J. of Mathematical Biology (2002) 44
p107-128.
- EA. Gaffney, On Conditions For The Stability
Of A Two Component Mixed Quasimonotone Reaction Diffusion
Equation, J. of Mathematical Analysis and
Applications (2001) 256,
p513-524.
- EA Gaffney, PK Maini, JA Sherratt, S.Tuft,
The Mathematical Modelling Of Cell Kinetics In Corneal
Epithelial Wound Healing
And Comparison With Experiment, Journal of Theoretical Biology (1999) 197,
p15-40.
- EA Gaffney, PK Maini, C. McCaig, M. Zhao, J.
Forrester, Modelling corneal epithelial wound closure in the
presence of
physiological electric fields via a moving boundary
formalism, IMA Journal of Mathematics Applied in
Medicine and Biology
(1999) 16, p369-393.
- E. Crampin, EA Gaffney, PK Maini, Reaction
and Diffusion on Growing Domains: Scenarios for Robust
Pattern Formation, Bulletin Mathematical Biology (1999) 61,
p1093-1120.
- EA
Gaffney, PK Maini, JA Sherratt, PD Dale, Wound healing in
the corneal
epithelium: biological mechanisms and mathematical models, Journal of Theoretical Medicine (1997),
1:13-23.
- EA Gaffney, Massive hard thermal loops in curved
space-time, Nuclear Physics B (1996) 476: 275-309.
- EA Gaffney, Quark hard thermal loops in curved spacetime,
Nuclear Physics B (1996) 459:311-334.
- J Frenkel, EA Gaffney, JC Taylor, High-temperature field
theory in curved spacetime, Nuclear Physics B (1995) 439: 131-143.
-
E Gaffney, Hard Thermal Loops, Weak Gravitational Fields and
The Quark
Gluon Energy Momentum Tensor, Nuclear Physics B (1995) 442: 268-298.
Book Chapters/Proceedings
- Dvoriashyna, M., Foss, A.J.E., Gaffney, E.A and
Repetto, R. 2022. Mathematical models of water transport
across ocular epithelial layers in ‘Modelling of Mass
Transport Processes in Biological Media’ edited by Sid
Becker, Andrey Kuznetsov, Filippo de Monte, Giuseppe
Pontrelli and Dan Zhao. Publisher: Elsevier. ISBN:
978044315653
- K
Ishimoto, EA Gaffney, Modelling Spermatozoan Swimming: Its
Capabilities
and Limitations for Contributing to The Understanding of
Sperm
Guidance, Flagellar mechanics and sperm guidance, Ch.9,
Flagellar
mechanics and sperm guidance, Ed. J. Cosson, Bentham Science
Publishers, (2015).
-
PK Maini, TE.Woolley, EA Gaffney, RE Baker, Turing's Theory
of
Developmental Pattern Formation, The Once and Future Turing,
Ch 9,
p137-149, edited by S.B. Cooper & A. Hodges, Cambridge
University
Press 2015
-
AA
Al-Shammari, EA Gaffney, S Egginton, Modelling Oxygen
Capillary Supply
to Striated Muscle Tissues, in Springer Proceedings in
Mathematics &
Statistics 87, Advances in Applied Mathematics, 2014
-
Shum H, Gaffney EA. Ch.2 in: MJ Kim, E Steager, A Agung
Julius eds. Mathematical models for individual swimming
bacteria
in Microbiorobotics: biologically inspired microscale
robotic systems.
Elsevier, 2012. ISBN: 9781455778911
-
M Kwiatkowska, G Norman, D Parker, O Tymchyshyn, JK Heath,
EA Gaffney,
Simulation And Verification For Computational Modelling Of
Signalling
Pathways, Proceedings of the 2006 Winter Simulation
Conference, L. F.
Perrone, F. P. Wieland, J. Liu, B. G. Lawson, D. M. Nicol,
and R. M.
Fujimoto, eds, (2006)
-
JR
Blake, EA Gaffney, Modelling aspects of tracer transport in
muco-ciliary flows, In Cilia, Mucus and Mucociliary
Interactions, 26, M
Salathe (Editor), New York, Marcel Dekker, 291-302. (2001).
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