Papers

Publications/preprints can be found on Google Scholar and ResearchGate.

Manuscripts

  1. Graph-Facilitated Resonant Mode Counting in Stochastic Interaction Networks

    Adamer MF, Woolley TE, Harrington HA

  2. Tensors and algebra give interpretable groups for crosstalk mechanisms in breast cancer

    *Seigal A, *Beguerisse-Díaz M, Schoeberl B, Niepel M, Harrington HA

  3. The topological "shape" of Brexit

    Stolz BJ, Harrington HA, Porter MA

  4. The geometry of sloppiness

    Dufresne E, Harrington HA, Raman DV

  5. Decomposing the parameter space of biological networks via a numerical discriminant approach

    Harrington HA, Mehta D, Byrne HM, Hauenstein JD

  6. Differential algebra for model comparison

    Harrington HA, Ho KL, Meshkat N

  7. Publications

  8. Roadmap for the computation of persistent homology

    Otter N, Porter MA, Tillmann U, Grindrod P, Harrington HA.

    EP J Data Science (In Press) arXiv:1506.08903.
  9. Nanog fluctuations in Embryonic Stem cells highlight the problem of measurement in cell biology

    Smith RCG, Stumpf PS, Ridden SJ, Sim A, Filippi S, Harrington HA, MacArthur BD

    Biophys J 2017 112(12):2641-265 biorxiv. doi.
  10. Persistent homology of time-dependent functional networks constructed from coupled time series

    Stolz BJ, Harrington HA, Porter MA

    Chaos 2017 27, 047410 arXiv:1506.00562. doi.
  11. The Role of the Hes1 Crosstalk Hub in Notch-Wnt Interactions of the Intestinal Crypt

    Kay SK, Harrington HA, Shepherd S, Brennan K, Dale T, Osborne JM, Gavaghan DJ, Byrne HM

    PLoS Comput Biol 2017 13(2): e1005400 arXiv:1608.06146. doi.
  12. Reduction of dimension for nonlinear dynamical systems

    Harrington HA and Van Gorder R.

    Nonlinear Dynamics 2017 88(1):715-734 arXiv:1508.05921.
  13. Numerical algebraic geometry for model selection and its application to the life sciences

    Gross E, Davis B, Ho KL, Bates DJ, Harrington HA.

    J R Soc Interface 2016 13:20160256 arXiv:1507.04331. doi.
  14. Role of seasonality on predator-prey-subsidy population dynamics

    Levy D, Harrington HA and Van Gorder R.

    J Theor Biol 2016 396:163-181. doi.
  15. Algebraic systems biology: a case study for the Wnt pathway

    Gross E, Harrington HA, Rosen Z, Sturmfels B.

    Bull Math Biol 2016 87(1):21-51. arXiv:1502.03188. doi.
  16. Topological data analysis of contagion maps for examining spreading processes on networks

    *Taylor D, *Klimm F, Harrington HA, Kramar M, Mischaikow K, Porter MA, Mucha PJ.

    Nat Commun 2015 6:7723. arXiv:1408:1168. doi.

  17. Phosphorelay in non-orthodox two component systems in-vivo functions through a bi-molecular mechanism: the case of ArcB

    Jonanovic G, Sheng X, Ale A, Feliu E, Harrington HA, Kirk P, Wiuf C, Buck M, Stumpf MPH.

    Molecular BioSystems 2015. doi.
  18. Parameter-free methods distinguish Wnt pathway models and guide design of experiments

    MacLean AL, Rosen Z, Byrne HM, Harrington HA.

    Proc Nat Acad Sci. 2015 Mar;112(9):2652-2657.arXiv:1409.0269. doi.
  19. Epithelial-Mesenchymal Transition in Metastatic Cancer Cell Populations Affects Tumor Dormancy in a Simple Mathematical Model

    MacLean AL, Harrington HA, Stumpf MPH, Hansen M.

    Biomedicines 2014 2(4):384-403. doi.
  20. Nuclear-cytoplasmic shuttling of ERK provides a switch-like transition between proliferation and differentiation of muscle progenitors

    Michailovici I, Harrington H, Azogui HH, Yahalom-Ronen Y, Plotnikov A, Ching S, Stumpf MPH, Klein OD, Seger R, Tzahor E.

    Development 2014 Jul;141(13):2611-20. doi.
  21. Cellular compartments cause multistability and allow cells to process more information

    *Harrington HA, *Feliu E, Wiuf C, Stumpf MPH.

    Biophys J. 2013 April;104:1824-1831. arXiv:1210.2993. doi.
  22. Clinical drug resistance linked to inter-convertible phenotypic and functional states of tumor-propagating cells in multiple myeloma

    Chaidos A, Barnes C, Cowan G, May P, Melo V, Hatjiharissi E, Papaioannou M, Harrington H, Doolittle H, Terpos E, Abdalla S, Yarranton H, Naresh K, Foroni L, Reid A, Rahemtulla A, Stumpf M, Roberts I, Karadimitris A.

    Blood. 2012 Nov 20. doi.
  23. A parameter-free model selection criterion based on steady-state coplanarity

    *Harrington HA, *Ho K, Thorne T, Stumpf MPH.

    Proc Nat Acad Sci. 2012 Sept;109(39):15746-15751.arXiv:1109.3670. doi.
  24. Mathematical modeling reveals the functional implications of the different nuclear shuttling rates of Erk1 and Erk2.

    Harrington HA, Komorowski M, Beguerisse-Díaz M, Ratto GM, Stumpf MPH.

    Physical Biology. 2012 9(3):036001.arXiv:1110.3742. doi.
  25. Skin barrier homeostasis in atopic dermatitis: feedback regulation of kallikrein activity.

    Tanaka RJ, Ono M, Harrington HA.

    PLoS One. 2011 6(5):e19895. doi.
  26. Bistability in apoptosis by receptor clustering

    Ho KL, Harrington HA.

    PLoS Comput Biol. 2010 6(10): e1000956.arXiv:0912.1548. doi.
  27. Coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype

    Boyle J, Harrington HA, Piper E, Elderfield K, Stark J, Landis RC, Haskard DO.

    Am J Pathol. 2009 Mar;174(3):1097-108.doi.
  28. Construction and analysis of a modular model of caspase activation in apoptosis

    Harrington HA, Ho KL, Ghosh S, Tung KC.

    Theor Biol Med Model. 2008 5:26. doi.
  29. A hybrid model for tumor-induced angiogenesis in the cornea in the presence of inhibitors

    Harrington HA, Maier M, Naidoo L, Whitaker N, Kevrekidis PG.

    Math and Comput Model. 2007 Aug;46(3-4):513-524. doi.
  30. Peer-reviewed book chapters

  31. Geometric combinatorics and computational molecular biology: Branching polytopes for RNA sequences

    Drellich E, Gainer-Dewar A, Harrington HA, He Q, Heitsch C, Poznanovic S.

    Accepted (to appear AMS Contemporary Mathematics Volume). arXiv:1509.04090.
  32. Mathematical and Statistical Techniques for Systems Medicine: The Wnt Signaling Pathway as a Case Study

    MacLean AL, Harrington HA, Stumpf MPH, Byrne HM.

    Systems Medicine. Editors: U Schmitz and and O Wolkenhauer, (2016) Springer. arXiv:1502.01902. doi.
  33. Outreach

  34. Teach Network Science to Teenagers

    Harrington HA, Beguerisse Díaz M, Rombach, MP, Keating LM, Porter AP.

    Network Science 2013 Sept;2:1-22.arXiv:1302.6567. doi.
    * = joint first authors